Endocrine Abstracts

Purpose: For vaginoplasty of Rokitansky syndrome, we use oxidized regenerated cellulose instead of bio-craft that has been used in the past because it requires a less invasive and more physiological surgery. However, the mechanism of epithelialization of this procedure is still not clear. There is a report that differentiation and proliferation of the vaginal epithelium of newborn mice is promoted by administration of basic fibroblast growth factor (bFGF).<p class="abstext...

Backgrounds: Podocytes are highly specialized postmitotic kidney cells that contribute to maintaining the filtration barrier and normal structure of glomerular capillaries. The (pro)renin receptor (PRR), as ATP6AP2, is an accessory subunit of the vacuolar H+-ATPase (V-ATPase), implying more fundamental, developmental functions for the PRR in addition to its role in activating the local renin-angiotensin system.Results: Podocyte-specific conditional (P)RR...